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Are these recommendations realistic? What do the prescribers of these drugs, the dermatologists and rheumatologists, think? In a survey of 325 UK dermatologists response rate 70% ; , 30 respondents reported that they had encountered ocular side effects of antimalarials, which were mild in most cases.32 However, of a random sample of 300 US rheumatologists listed in the directory of the American College of Rheumatology, 75% stated that they would continue to screen for hydroxychloroquine retinopathy because they were unwilling to accept any risk of visual loss among their patients, 74% would continue to screen because of legal liability, and 56% felt that their patients would insist on being screened regardless of their physician's opinion.33 A total of 44% stated that they would continue to screen regularly even if the College published guidelines discouraging routine screening. A recent survey of all ophthalmologists in Texas showed that 77% follow patients receiving hydroxychloroquine therapy every 6 months.34 A total of 122 respondents 42% ; had diagnosed hydroxychloroquine toxicity in at least one patient; of the 122, 37 30% ; had had a patient with permanent visual loss from hydroxychloroquine. CONCLUSION At least in North America, surveys of dermatologists, ophthalmologists and rheumatologists suggest that some screening of patients taking antimalarials is indicated, as cases of definite retinopathy have been reported in patients receiving less than the recommended dosage. It appears reasonable to perform a baseline examination, including determination of visual acuity, Amsler grid or Humphrey 10-2 white testing or both, and colour vision testing within the first year of therapy. If patients are at low risk Table 1 ; , an examination after 5 years of therapy seems reasonable. Despite guidelines and recommendations.
Competi tion between dehydrocholic acid and bromosulfophthalein, and rose bengal dye" and bromosulfophthalein and probenecid.16 The interference phenomenon between an oral cholecystographic agent and bromosulfophthalein has been ohserved, '5.
Ghizzoni AM, Pegoraro C, Zadro R. Sviluppo operativo: "Carta Qualit Percepita" Asl di Mantova. QA 2002; 1: 3753. Eurisko. La qualit percepita dei servizi sanitari pubblici in Italia, 2000. Censis. Indagine annuale del monitor Biomedico, 2003. Progetto qualit percepita. ospedaleudine European Observatory on Health Care Systems. Health Care in Transition Series Health Care Plans of Denmark, Finland, Italy, Spain, Sweden, Austria, Germany ; . European Union. National report on Consumer Policy. Coulter A. Patients' charters. Health Expectations 1999; 2 3 ; : 14749. Hogg C. Patients, Power and Politics. Sage Publishing Company, 1999. Hogg C, Williamson C. Whose interests do lay people represent? Towards an understanding of the role of lay people as members of committees. Health Expectations 2001; 4: 29. Roberts KJ. Patient empowerment in the United States: a critical commentary. Health Expectations 1999; 2 Saltman RB, Figueras J. European Health Care Reform. WHO Europe, 1997. Suchman AL, Botelho RJ, Hinton-Walker P. Partnerships in Healthcare. University of Rochester Press, 1998. Shaw CD, Kalo I. A background for national quality policies in health systems. Health documentation services, WHO Regional Office for Europe, Copenhagen, 2000. Geboers H, Mokkink H, Von Montfort P, Van Den Hoogen H, Van Den Bosch Wil, GroR. Continuous quality improvement in small general medical practices: the attitude of general practitioners and other practice staff. International journal for Quality in Health Care 2001; 13 5 ; 39197. Bankauskaite V, Saarelma O. Why are people dissatisfied with medical care services in Lithuania? A qualitative study using responses to open-ended questions. International journal for Quality in Health Care 2003; 15 1 ; 2329. Lee AH, Boldy D., Chou SC. Measuring job satisfaction in residential aged care. International journal for Quality in Health Care 2002; 14 1, ; 4954. Entwistle V. Exploring patient participation in decision-making: the views and experience of patients in diverse clinical contexts. Health Services Research Unit, Aberdeen University Ian Watt, Department of Health Sciences, University of York. Berney L, Curtis S, Doyal L, Feder G, Griffiths C, Hillier S, Rees Jones I, Kelly M, Rink P, Rowlands G. Decision-making in primary care: patients as partners in resource allocation. London: St. George's Medical School, 2003. Elwyn GJ, Edwards A, Kinnersley P. Shared decision making in primary care: the neglected second half of the consultation. British Journal of General Practice 1999; 49: 47782. Lewin SA, Skea ZC, Entwistle V, Zwarenstein M, Dick J. Interventions for providers to promote a patient-centred approach in clinical consultations Cochrane Review ; . In: The.
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Helle Rasmussen, Informationskoordinator Discussion: Seeking religious help for mental disorders is often a first step in the management of mental disorders as a result of cultural explanations for the illness. This behavior also has social sanctions. Key Words: chronic mental illness - religious sites - qualitative study - ritualistic practices International journal of social psychiatry 51 2 ; , 139-149, 2005.
Species reached only about 5% the maximum was 30% at Basel railway station in 2002 Hnggi and Heer, unpubl. ; . Displacement of native spider species has not been recorded and would be very difficult to prove. Such studies would involve standardized experiments at the same field site over decades, with year-round sampling and also Swiss-wide sites for comparative work. Funding for this kind of research seems unlikely, although the samples could be used for other arthropod research. Zodarion italicum Canestrini ; The origin of the aptly named Zodarion italicum is the south of Europe. It has expanded its distribution since the publication of the catalogue of Swiss spiders Maurer and Hnggi, 1990 cited as sub Z. gallicum ; , and has since reached the south of Switzerland. It is possible that it is even native to that region see, e.g., Lessert, 1910 ; . This spider is a highly specialized predator of ants Pekar and Kral, 2002 ; and occurs mainly in open habitats. The rapid expansion of its range is probably attributable to human-mediated transport to new areas and to global warming, which allows species of southern origin to survive north of the Alps. However, this probable relationship would be difficult to demonstrate. The species is also expanding its range in Germany, as is its sister species Z. rubidium Simon see Bosmans, 1997; Staudt, 2004; also see Figure 5.1 ; . Other species found in natural habitats Besides the two species mentioned above, a number of other species are spreading in Central Europe, or their spread is likely within the next few years. A selection of these species is discussed below. Collinsia inerrans O.P.-Cambridge ; syn. Milleriana inerrans, C. submissa ; has been found locally in Switzerland during the last 50 years. Currently, the species is expanding its range in western Germany Klapkarek and Riecken, 1995 ; , and has reached the north-east of Bayern Blick, 1999 ; . However, it has not yet reached the abundance of Eperigone trilobata, despite their similarities in size and ecological niche. The future expansion of this species in Switzerland should be monitored. Ostearius melanopygius O.P.-Cambridge ; : Ruzicka 1995 ; portrays the spread of this cosmopolitan species of unknown origin cryptogenic ; in Europe. In Switzerland, a similar pattern as for C. inerrans has been observed. However, occasionally the species exhibits mass outbreaks, which can be a nuisance to humans although it does no actual harm Sacher, 1978 for cases in Switzerland see, e.g., Benz et al. 1983 ; . The normal sampling techniques using traps at ground level are not effective under these circumstances and generally catch only single individuals. The reasons for the mass outbreaks are not yet understood. The distribution of Harpactea rubicunda C.L. Koch ; described by Wiehle 1953 ; was restricted to the eastern part of Germany at that time. Since then, the species has expanded its range considerably westwards, most probably by human-mediated transport. It occurs in houses as well as in other synanthropic habitats. In Switzerland, the species was found near Zurlinden Hnggi, 1988 ; and in a disused railway area at Basel Hnggi and Weiss, 2003 ; . Erigone autumnalis Emerton, like Eperigone trilobata, originates in North America. The species has been found at several locations in Switzerland Maurer and Hnggi, 1990; Hnggi, unpubl. ; . However, it seems to be less abundant and covers a smaller range than E. trilobata. Nesticus eremita Simon can be found outdoors around Basel Hnggi and Weiss, 2003; Hnggi, unpubl. ; , whereas further north the species is restricted to underground canals and artificial caves Jger, 1995, 1998; Blick, unpubl. ; . It is very likely that this southern European species will expand its range further in the near future. Cicurina japonica Simon ; : this spider of JapaneseChinese origin was not accepted as an established spider species in Germany by Platen et al. 1995 ; , since the introduction of the species near Kehl Rhein was thought to be temporary. Since then, fairly large populations have been found in the area around the railway at Basel Hnggi and Heer, unpubl. ; . This indicates that the species is able to establish in Europe and the further development of its populations should be monitored. Diplocephalus graecus O.P.-Cambridge ; : Blick et al. 2000 ; presents a record of this species of Mediterranean origin from agricultural areas near Paris, France. Today the species has reached.
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SORL1 Gene Discovery Nature Genetics January 15, 2007 SORL1 is a gene that is strongly associated with risk for the most common type of Alzheimer's late onset sporadic disease ; in populations of several ethnic groups. the SORL1 gene controls proteins that act like "delivery boys, " moving the amyloid parent protein APP ; to different places in the brain cell. In one place on the cell, APP is broken down into the toxic beta amyloid that forms the plaques found in Alzheimer's. In other places on the cell it is broken down into innocuous pieces. SORL1 favors the "good" pathway innocuous breakdown.
134603, 134604. Merged into one single registration bearing the registration number 134603 and covering classes numbers 24, 25. SUPIMA ASSOCIATION OF AMERICA and ibandronate.
The load incrementation procedures in this analysis were set for each model in order to reduce the elapsed time of the analysis. 1 unit load was applied in the vertical direction at the shear span, Ls from the support. The starting load factor was set as 100 and the slab was loaded until the maximum load factor or the maximum number of increments was achieved. Figure 3.9 shows that the FE analysis result stops before reaching plateau. This is because maximum material properties for the concrete and steel deck are achieved for the load applied. For further load application, LUSAS cannot solve the problem mathematically and the analysis is terminated!
| Hydroxychloroquine and pregnancyClinical study involving 35 patients with Q fever endocarditis, the addition of hydroxychloroquine to doxycycline was found to reduce the median duration of treatment by 2 years compared to treatment with doxycycline and ofloxacin, and there were no relapses after 18 months of therapy in the group that received hydroxychloroquine-doxycycline 30 ; . The mortality rate for both regimens was 5%, and the major complication associated with each regimen was hypersensitivity to sunlight. Adverse effects of hydroxychloroquine include photosensitivity and retinal accumulation, but only 1 of 21 patients in the doxycycline-hydroxychloroquine group developed retinal toxicity that required the discontinuation of hydroxychloroquine treatment 30 ; . Although the optimal duration of therapy is unknown, based on these findings, the current recommendations for the treatment of chronic Q fever are 100 mg of doxycycline by mouth twice daily with 600 mg of hydroxychloroquine by mouth once daily for at least 18 months. Serologic testing is recommended on a regular basis during therapy, and the main predictive criterion of clinical cure is a decrease of phase I IgG antibody titers to 200 28 ; . Because Q fever is an occupational hazard, vaccination has been advocated for exposed populations, including livestock handlers, abattoir workers, persons in contact with unpasteurized dairy products, veterinarians, and laboratory personnel working with C. burnetii 23 ; . Although clinical data are lacking, vaccination should also be considered for persons who are not professionally exposed but who are at higher risk for development of chronic Q fever, including those with cardiac valve defects or prostheses, those with vascular aneurysms, and immunocompromised patients. Currently available vaccines, which are produced from phase I whole-cell C. burnetii isolates, are effective in protecting humans against infection, but vaccination of people with preexisting immunity can induce severe local and occasional systemic reactions 39 ; . Existing Q fever vaccines for humans and animals are not commercially available in the United States. For unclear reasons, C. burnetii infection is less commonly recognized in the United States than in other developed countries, and cases of chronic Q fever are extremely rare. However, recent seroepidemiologic studies indicate that this infection is highly prevalent among U.S. cattle 12 ; , and a recent national survey of infectious disease experts reported that as many as 75% of diagnosed Q fever cases are not reported, and many cases are likely not diagnosed 10 ; . Since Q fever became reportable nationally in 1999, there has been a linear increase in the numbers of human cases identified, with 21, 26, 61, and 70 cases in each year from 2000 through 2004 11 ; . As August 2005, 65 cases of Q fever were diagnosed in the United States in 2005, extrapolated to 110 cases over the entire year. Thus, it is likely that the prevalence of Q fever in the United States is not dissimilar to that observed in other countries where it is considered a significant and frequent cause of disease. Because affected patients may have nonspecific symptoms with no history of direct farm exposure and atypical echocardiographic findings, the diagnosis of chronic Q fever should be considered for all individuals with heart valve lesions or immunosuppression who present with unexplained fever and ibritumomab.
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Table 1 Percentage frequency of presenting clinical features in patients with SLE from different regions in India Manifestations Northern Southern Western Eastern Central Mean 10 11 12, n 329 ; n 330 ; n 315 ; n 192 ; n 200 ; Arthritis Fever Skin lesions Nephritis Raynaud's Oral ulcers Neuropsychiatric Gastrointestinal Lymphadenopathy Cardiac Thrombocyto-paenic purpura 57 44 36 * 1st * 3rd * NA NA 4th * NA NA NA 50.6 45.
ALP in a subgroup of 10 cardiac-surgery patients for 10 days postoperatively showed initial decreases, with gradual recovery to near-normal values by the 10th day. That the changes in Mg and ALP seen postoperatively were not attributable to hemodilution alone was confirmed by measuring total-protein concentrations before and after operation. ALP requires Mg ion in vitro for optimal activity, but addition of Mg in the appropriate amounts to sera with low ALP activity did not restore ALP activity. The low ALP activity seen in postcardiac surgery patients in vivo may perhaps be related to factors other than Mg that were removed by the cardiopulmonary bypass pump. Addftlonal Keyphrases: magnesium alkaline phosphatase total protein cardiopulmonarybypass general and spinal anesthesia and idarubicin.
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Submitted by Joe Beach, Secretary The Rocky Mountain Hang Gliding and Paragliding Association had its annual Awards Banquet and January meeting at 5: 00pm on 15 January 2005 at CB & Potts on 120th Avenue in Denver. The first few hours were spent socializing and having dinner, and then we moved in to a short discussion of current news and the presentation of awards. After the awards and raffle, we showed some videos and "shot the breeze" some more. Several people were still carrying on conversations when I left at 9: 30pm. New Over-Under Tow Release. Dave Neimeyer has been developing a new over-under two release. Over-under releases are very nice for powered winch or payout winch hang glider towing. They allow the pilot to start the tow with the line passing over the base tube, but then switch to having it pass below the base tube as the pilot gains altitude. This eliminates the problem of having the tow line press against the base tube as the tow line angle changes during the tow. The over-under releases we are currently using are about 12 inches long. Dave's new design is much more compact, about 4 inches long. He has a prototype model that he and other pilots are testing. Powered winch tow. Dave Neimeyer and Tim Denton have been working on their new powered winch tow. Mark Windsheimer has been helping them with the design. They expect to have enough power to easily pull tandem tows, and have 10, 000 feet of tow line. Now they just need to find a place where they can lay out that much line. First Aid CPR clinic. Craig Thompson invited people to attend a first aid and CPR clinic on 29 January. Contact him to sign up. Participation in the cross country competition. It was pointed out that quite a few people who had good cross country flights this year did not submit them for consideration in the cross country competition. Tim Denton and Jim Yocom are going to try to increase participation in the contest by offering monthly flying gear prizes for turning in flights and perhaps some cash prizes. The competition is open to all RMHGPA pilots, and has no entry fee. Flights are weighted so paragliders and hang gliders can compete on equal footing. The full set of rules are on the web site. Awards. We voted for the awards by a show of hands. The awards and their winners were: Golden Hammer. This is given to a pilot that had a memorable "hard landing" that resulted in glider damage but no pilot damage. Shawn Banks graciously accepted it for a rough landing he had at Lookout after a long 3 + hour ; and tiring flight. Most Improved Pilot. B. J. Herring was declared the Most Improved Pilot for his increased discretion with regard to acceptable flying conditions in the past year. Mentor of the Year. Mike Wiman was recognized as the Mentor of the Year for all of the time he spends helping people when they are towing. Most Valuable Member. Kay Tauscher was named the Most Valuable Member for all of her effort with Boulder Open Space and Mountain Parks during the past year. Safe Pilot. Jim Yocom was given the Safe Pilot award for his good judgment when deciding when to fly. Driver of the Year. Kieran O'Donovan was declared the Driver of the Year for his generous retrieves at this year's Barney Fly-in at Dinosaur. He made a nearly 300 mile round trip to pick up Tim Denton, and almost received a trespassing ticket when he accidentally drove on a private road to pick up Brett Hoglan. Bushwacker. This award is given to a pilot makes a crosscountry flight that ends with a difficult retrieve. There was quite a bit of debate over whether Brett Hoglan and Tim Denton most deserved this award. In the end, Tim Denton received it in recognition of a flight at Dinosaur that resulted in a particularly long equipment-laden hike to get back to a road. Longest flight during the Brad Koji Fly-in. Marie Lothon recorded the longest flight during the Brad Koji Fly-in this year. It started at Dinosaur, and was 41 miles. She is currently in France, so Jim Yocom will be keeping the traveling trophy for her. Longest flight from Lookout. Jim Yocom submitted the longest flight from Lookout this year, which was 28 miles. Class A cross country award. This is the "open class" award in the RMHGPA cross country competition, and is awarded to the pilot who had the highest scoring 3 flights for the year. Tim Denton won it with three flights totaling 334 points. Class B cross country award. This class is open to pilots whose previous longest flight was less than 50 miles. It was won by John DeGraaf, with 54.5 points. Class C cross country award. This class is open to pilots whose previous longest flight was less than 10 miles. It was also won by John DeGraaf.
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FIG. 1. Pharmacokinetics of uridine after a single oral dose of 1, 000 mg kg. F, Patient 1. OE, Patient 2. s, Control.
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CHAPTER 2 PATIENT POTENTIAL 17. Definition of the disease 17 Segmentation of RA 21 and northern Europe show a higher prevalence of RA across the seven major markets 21 Average RA clinical trial participant is over 50 and female 22 Decrease in RA severity due to better treatment but epidemiology research continues 24 Key epidemiology studies in RA in the US, EU and Japan 26 2005 studies are coming from France and Canada but key Japanese studies need updating 26 US 26 Europe 30 Japan 32 Statistical caveats 33 Prevalence versus incidence 33 Diagnosed versus undiagnosed prevalence 34 Different methods of gathering prevalence data 34 Data ranges 34 Unmet need in RA is still headed by efficacy 35 Clinical unmet needs 36 Efficacy 36 Side effects 36 Administration and patient compliance 38 Cytokine assays a key challenge for treatment development 38 Environmental unmet needs 39 Cost 39 CHAPTER 3 R&D APPROACH 42. The current treatment approach puts biologic therapy after different combinations of traditional DMARD treatments 43 Current market definition includes the most common biologic and traditional DMARDs 44 The Japanese market 45 The market value is calculated using IMS diagnosis value 45 Classification of pipeline products 46 Cytokines 46 Interleukins 47 TNF inhibitors 50 Cell adhesion molecule inhibitors 51 MAP kinase 52 Immunomodulators 53 Other chemokines 56 Clinical trial design 57 Clinical trial endpoints in RA 59 American College of Rheumatology ACR ; measures are the most common endpoints 59 Disease Activity Scale 59 Tender Joint Count and Swollen Joint Count 60 Quality of Life Questionnaires 61 HAQ 61 Medical Outcome Short Form 36 SF-36 ; Health Survey 62 Blood testing 62 Erythrocyte sedimentation rate ESR ; 62 C-reactive proteins CRP ; 62 Disease progression 62 CHAPTER 4 RA PIPELINE ANALYSIS 64. Pipeline overview 64 Pre-registration and Phase III 66 Phase II 67 Key companies involved in the RA pipeline 70 Roche dominates the late-stage pipeline 70 Sanofi-Aventis is a key player in traditional DMARDs but has not broken into the biologic arena 72 and iloprost.
Redman, Mary Ann Infant dies of dysentery, 09 15 1854: Redman Mr ; New York man starves to death, 03 27 1858: Reed, A. Amelia Wed to Charles Willis Harding, 08 10 1861: Reed, Allen Lakeville man dies at age 61, 04 21 Reed, Apollos Administrator petitions to sell real estate, 10 29 1864: Administrator's sale, 11 16 1867: Administrator's first account of estate, 03 21 1868: Reed, Apollus Commissioners' notice, 08 13 1864: Reed, Appollos Dies at age 72, 09 12 Reed, Benj. H. Wed to Emily F. Shaw, 12 13 1862: Reed, B.F.H. Wed to Ruth H. Sherman, 01 08 1859: Reed, Charlotte Wife of Henry W. dies at age 27, 11 04 Reed, Charlotte T. East Bridgewater woman dies at age 48, 08 15 Reed, Cyrus P. Wed to Nancy M. Clark, 07 20 1855: Reed, Diana Wed to Benjamin A. Pratt, 06 12 1858: Reed, Ebenezer East Abington man dies at age 74, 08 13 Reed, Edward P. Wed to Georgiana S. Loud, 09 24 1864: Reed, Emily B. Wed to Henry Copeland, 12 24 1864: Reed, Francana E. Church organist acknowledges gift, 11 02 1861: Reed, Frances L. Taunton woman dies at age 26, 05 22 Reed, Franklin South Abington man dies at age 24, 05 12 Reed, Frederick D. Wed to Mary Augusta Holmes, 01 20 1866: Reed, Hannah Guardian Job Nelson request sale of real estate to cover upkeep, 10 12 1855: Guardian sale, 03 14 1856: Berkley woman dies at age 76, 04 11 Estate creditors to meet, 10 1856: Administrator's notice, 05 08 1857: Reed, Harriett D. Wed to John R. Mirick, 04 09 1859: Reed, Ichabod T. Famous local son, "Fat Boy, " dies, 09 08 1854: Dies at age 23, 09 08 Reed, Isaac Oldest East Bridgewater resident dies at age 92, 10 26 Reed, Isaac N. Wed to Abigail Williams, 10 30 1857: Lakeville man dies at age 24, 11 19 Reed, Isodor Wed to Ruby R. Rockwell, 12 03 1859: Reed, James C. Wed to Georgianna M. Dorr, 08 01 1868: Reed, J.D. Clothes stolen by night thieves, 10 22 1859: Reed, Jeremiah W. Auction sale, 01 16 1858: Injured loading logs, 06 15 1867: Reed, John Sells 14-year-old elm to Wood, transplants successfully, 04 03 1858: Wed to Susan A. Shaw, 07 09 1859: West Bridgewater native dies at age 79, 12 01 Bridgewater man dies at age 79, 12 01 Reed, John A. Wed to Abbie F. Chace, 06 25 1859: Reed, John C. House and farm for sale, 05 25 1855: Poor House bridge bid 5, 07 16 1859: Taking up Poor House bridge, 09 10 1859: Cow killed on railroad track, 09 24 1859: Reed, John D. Wed to Helen F. Sproat, 07 15 1865: Reed, John E. Chosen in third supplementary draft, 07 09 1864: Exempted from service, 08 06 1864: Reed, Joseph Wed to Polly C. Phinney, 10 29 1859: Reed, Joseph B. Wed to Elizabeth T. Williams, 12 05 1856: Reed, Joseph, Jr. Boston man dies on board steamer Empire State, 08 01 1856: Reed, Levi Dies at age 54, 04 30 Reed, Levi, Jr. Lakeville man dies at age 34, 02 16 Reed, Lizzie M. Bridgewater infant dies, 09 1865: Reed, Lois Widow of Nathan dies at age 90, 03 16 Reed, Lorenzo Wed to Vesta A. Hunt, 01 25 1868: Reed, Louise Bradford North Bridgewater infant dies, 10 28 1865: Reed, Lucy Using old-fashioned spinning wheel every day, 01 05 1867: Reed, Lucy D. Widow dies at age 81, 08 31 Reed, Luke, Jr. Goes into jewelry business, 08 01 1856: Jewelry, port monnaies, etc. ad ; , 08 1856: Wed to Francena E. Pratt, 01 05 1861: Reed, M. Wounded at Battle of Fredericksburg, 01 03 1863: Reed, Marcus M. Pembroke soldier dies at Brashear City, 08 15 1863: Reed, Mercy Adaline Daughter of John C. and Mercy B. dies at age 1, 05 15 Reed, Milton E. Wed to Nettie C. Raymond, 09 14 1867: Reed Mr ; Company D soldier home on furlough, 02 14 1863: Reed Mrs ; Wife of James dies, 06 09 1854: Reed, Mrs Samuel East Abington woman dies at age 62, 10 28 Reed, Nathan Wed to Lucinda Raymond, 08 05 1865: Reed, Nathaniel Middleboro man killed in Texas, 12 24 1859: Army Captain Bliss writes of Reed's service l ; , 01 28 1860: Reed, Nathaniel W. Farm for sale, 07 02 1859: Reed, Reuben Wed to Sarah S. Morse, 12 07 1855: Reed Rev ; Middleboro man pastor of Brewster Baptist Church, 12 14 1867: Reed, Samuel Dies at age 72, 04 23.
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